Computational Safety Pharmacology


LeadOp Computing develops innovative computational solutions to analyze the huge amounts of information generated in the field of drug discovery, with a focus on predictive toxicology in general and safety pharmacology in particular.

ePharmaProfiler, our leading product is going beyond the traditional QSAR data analysis methods to predicting toxicology. We are combining fragment-based analysis, systems biology and statistics to identify potential liabilities in novel chemical entities from the early stages. ePharmaProfiler focuses on small effects happening at pharmacological doses (side-effects).

The main advantage of our technology is to quickly provide scientists with potential mechanisms of action that can experimentally be evaluated under the financial and time constraints of drug discovery (low cost, fast turn-around).